Dr Stephen Hiscox

PhD, FHEA, School of Pharmacy and Pharmaceutical Sciences, Cardiff University

Steve Hiscox

Dr Hiscox is currently Senior Lecturer in Cancer Biology within the School of Pharmacy and Pharmaceutical Sciences, Cardiff University. He has a long-standing interest in cancer invasion and metastasis, the subject of his PhD at the School of Medicine in Cardiff, particularly in the context of drug resistance in a range of tumour types. The long term goal of his laboratory is to better understand the cellular and molecular pathways underlying metastasis in order to identify novel therapeutic targets. His research group is actively engaged in three themes of multidisciplinary, cancer-focused research:

• Exploring the role of non-receptor tyrosine kinases as mediators of drug response and resistance and understanding their value as therapeutic targets.

• Investigating the complex interplay within the tumour microenvironment, exploring how tumour cells interact with, and are influenced by, fibroblasts and bone cells and how these interactions can support metastases.

• Identifying molecular determinants of adverse response to targeted therapies and determining their potential for use as predictive biomarkers for cancer patients and therapeutic exploitation.

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